Arbovirus Antibodies, IgM, CSF
Also known as: ARBO CSF M
Use
This test is intended as a semi-quantitative means of detecting antibody to specific arboviruses, including West Nile virus, Eastern Equine Encephalitis, Western Equine Encephalitis, California Encephalitis, and St. Louis Encephalitis viruses in CSF samples. The detection of IgM antibodies in CSF may suggest active or recent central nervous system infection by the arbovirus.
Special Instructions
New York clients must be aware that this test is not New York state approved, and specimens will be sent to a New York state-approved lab. The test is not recommended as a stand-alone; instead, consider the Arbovirus Antibodies, IgG and IgM, CSF (2001597).
Limitations
This test should not be used solely for quantitative purposes and should correlate with clinical history and other data. Due to cross-reactivity within virus families, results indicative of one arbovirus infection may cross-react with another. Passive transfer of serum antibodies across the blood-brain barrier may also lead to detectable IgM in CSF.
Methodology
Immunoassay (ELISA)
Biomarkers
LOINC Codes
- 39573-1
- 10899-3
- 9316-1
- 49139-9
- 21510-3
Result Turnaround Time
1-5 days
Related Documents
For more information, please review the documents below
Specimen
Cerebrospinal Fluid
Volume
4 mL
Minimum Volume
1.5 mL
Container
ARUP Standard Transport Tube
Collection Instructions
Transfer 4 mL CSF to an ARUP Standard Transport Tube. (Min: 1.5 mL); New York State Clients: 1 mL CSF (Min: 0.1 mL) AND 2 mL CSF (Min: 0.7 mL)
Storage Instructions
Refrigerated. New York State Clients: Ambient as test code 60145 and Refrigerated as test code 36597
Causes for Rejection
Contaminated, heat-inactivated, or hemolyzed specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 8 hours |
| Refrigerated | 2 weeks |
| Frozen | 1 year |