Aspartate Aminotransferase, Serum or Plasma
Also known as: AST
Use
The Aspartate Aminotransferase (AST) test is used to assess liver function and detect liver damage. AST is an enzyme found primarily in the liver, heart, and muscles. Elevated levels of AST in the blood can indicate liver injury, heart damage, or muscle disorders. It is often measured alongside alanine aminotransferase (ALT) to differentiate between liver and cardiac conditions.
Special Instructions
This test is approved for use in New York state. Ensure that the serum tube clots completely at room temperature before processing. AST levels may be falsely elevated in hemolyzed specimens, so care must be taken to properly handle and process samples to avoid hemolysis.
Limitations
AST measurement may be influenced by factors such as hemolysis, medications, and the presence of other medical conditions that increase AST levels. Interpretation of AST results should consider the overall clinical context, including other laboratory findings and the presence of liver or heart abnormalities. The stability of serum or plasma samples is limited; they should be tested within specified time frames to ensure accuracy.
New York Approved
Methodology
Automated Analyzer (Clinical Chemistry)
Biomarkers
LOINC Codes
- 1920-8
- 1920-8
Result Turnaround Time
0-1 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.2 mL
Container
ARUP standard transport tube
Collection Instructions
Allow serum tube to clot completely at room temperature. Separate serum or plasma from cells within 2 hours of collection.
Storage Instructions
Refrigerated transport is required.
Causes for Rejection
Specimens containing sodium fluoride/potassium oxalate, or citrate. Hemolyzed specimens. Specimens containing cellular material.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 4 days |
| Refrigerated | 1 week |
| Frozen | 3 months |