Autoimmune Neuromuscular Junction Reflexive Panel
Also known as: MUWA R2
Use
The Autoimmune Neuromuscular Junction Reflexive Panel aids in diagnosing a broad range of acquired neuromuscular junction (NMJ) disorders. It is particularly useful for the evaluation of myasthenia gravis and other autoimmune diseases affecting the neuromuscular junction, such as Lambert-Eaton myasthenic syndrome and autoimmune autonomic ganglionopathy. The test includes various antibodies associated with these disorders, helping identify autoimmune involvement and assist in differential diagnosis.
Special Instructions
Not provided.
Limitations
This test was developed and its performance characteristics determined by ARUP Laboratories. It is intended for clinical purposes and has not been cleared or approved by the US Food and Drug Administration. Antibodies to other neuromuscular junction proteins may result in negative test results. Interpretation should be made in conjunction with clinical history and other diagnostic tests to accurately diagnose NMJ disorders.
New York Approved
Methodology
Immunoassay (Radioimmunoassay)
Biomarkers
LOINC Codes
- 49692-7 - Stria Mus IgG Ser Ql IF
- 11034-6 - AChR Bind Ab Ser-sCnc
- 33980-4 - VGCC-P/Q Bind Ab Ser-sCnc
- 42937-3 - AChR Block Ab/AChR Total SFr Ser
- 41871-5 - VGKC Ab Ser-sCnc
- 100371-4 - Titin Ab Ser IA-aCnc
- 33979-6 - VGCC-N Bind Ab Ser-sCnc
- 42233-7 - nAChR Ab Ser-sCnc
Result Turnaround Time
2-8 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
2 mL
Minimum Volume
1 mL
Container
Serum separator tube (SST)
Collection Instructions
Separate serum from cells ASAP or within 2 hours of collection.
Storage Instructions
Transport refrigerated.
Causes for Rejection
Plasma. Contaminated, hemolyzed, or severely lipemic specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 48 hours |
| Refrigerated | 2 weeks |
| Frozen | 1 year |
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