Babesia Species by PCR
Also known as: BABPCR
Use
The Babesia Species by PCR test is designed as a first-line diagnostic tool for acute babesiosis, a tickborne disease. It detects nucleic acid from Babesia microti and can also detect Babesia duncani, B. divergens, and Babesia strains MO-1 and EU-1. However, it cannot differentiate between these species and strains. The test is crucial for accurately diagnosing babesiosis, which can be life-threatening if not treated promptly. It is especially useful for patients presenting with symptoms consistent with babesiosis, such as fever, chills, and fatigue, particularly in endemic regions.
Special Instructions
Not provided.
Limitations
The Babesia Species by PCR test has certain limitations. A negative result does not rule out the presence of PCR inhibitors in the patient specimen or test-specific nucleic acid in concentrations below the level of detection by this test. Additionally, while nucleic acid from B. duncani, B. divergens, MO-1, and EU-1 strains will be detected, the test cannot differentiate between these species or strains beyond B. microti. There may also be limitations due to specimen quality and handling that could affect the detection sensitivity.
Methodology
PCR-based (PCR)
Biomarkers
LOINC Codes
- 88233-2 - Babesia DNA Bld Ql NAA+probe
- 21089-8 - B microti DNA Bld Ql NAA+probe
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Whole Blood
Volume
1 mL
Minimum Volume
0.6 mL
Container
Lavender (EDTA) or pink (K2EDTA) tube
Storage Instructions
Refrigerated
Causes for Rejection
Serum, plasma, and heparinized specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 24 hours |
| Refrigerated | 1 week |
| Frozen | 14 days |
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