Bartonella quintana Antibody, IgG by IFA
Also known as: QUINT G
Use
The Bartonella quintana Antibody, IgG by IFA test is designed to assist in confirming suspected Trench fever in patients who exhibit typical signs and symptoms consistent with the disease, as well as a compatible exposure history. A low positive result suggests past exposure or infection, while a high positive result may indicate an active or recent infection. However, the test is not conclusive for diagnosis based solely on a positive result, hence seroconversion between acute and convalescent sera, which is considered strong evidence of recent infection, should be evaluated. The test helps in the assessment of the presence of Bartonella quintana IgG antibodies to suggest current or past infection.
Special Instructions
For optimal results, it is advised to submit both acute and convalescent specimens for seroconversion evaluation. Parallel testing is preferred and the convalescent specimens must be received within 30 days from the receipt of the acute specimens. Specimens should be clearly marked as acute or convalescent.
Limitations
Despite positive results, the test may not conclusively diagnose Bartonella quintana infection. Seroconversion between acute and convalescent sera is a stronger indicator of recent infection. Variability in antibody levels due to previous exposures may obscure interpretation. The test results should be considered alongside other serological and clinical evaluations. Environmental factors such as contamination or hemolysis can potentially affect results. Additionally, repeat IFA testing within a 10-14 day window may aid interpretation for equivocal findings.
Methodology
Immunoassay (IFA)
Biomarkers
LOINC Codes
- 9360-9
Result Turnaround Time
1-8 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.4 mL
Container
ARUP standard transport tube
Collection Instructions
Separate serum from cells ASAP or within 2 hours of collection.
Storage Instructions
Refrigerated.
Causes for Rejection
Contaminated, hemolyzed, or severely lipemic specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 48 hours |
| Refrigerated | 2 weeks |
| Frozen | 1 year (avoid repeated freeze/thaw cycles) |
