CD10 (CALLA) by Immunohistochemistry
Also known as: CD10 IHC
Use
The CD10 (CALLA) by Immunohistochemistry test is used to identify the expression of the CD10 protein in tissue specimens. CD10 is a cell surface enzyme involved in the breakdown of signaling peptides, and its expression can be indicative of various neoplasms including certain lymphomas and leukemias, where it may serve as a diagnostic marker.
Special Instructions
This test is performed as a stain and return (technical) service only. Order requests should be submitted electronically, or via ARUP Immunohistochemistry Stain Form (#32978) for clients without electronic ordering capability. Use ARUP Client number for the order. The specimens must be formalin-fixed and paraffin-embedded.
Limitations
The test is limited to detecting the presence of CD10 protein expression and does not provide information on genetic or mutational status. False results may occur if specimen handling is inadequate, including non-representative tissue samples or improperly prepared cell blocks. Depleted specimens and slides that have been oven-baked are unacceptable for analysis.
New York Approved
Methodology
Immunoassay (IHC)
Biomarkers
LOINC Codes
- 94736-6
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
2 slides
Container
Tissue block or 5 unstained, positively charged slides
Collection Instructions
Formalin fix (10 percent neutral buffered formalin) and paraffin embed specimen. Protect paraffin block or slides from excessive heat. Do not oven bake precut slides.
Storage Instructions
Room temperature or refrigerated. Ship in cooled container during summer months.
Causes for Rejection
Depleted specimens. Non-representative tissue type.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Indefinitely |
| Refrigerated | Indefinitely |
| Frozen | Unacceptable |