CD103 by Immunohistochemistry
Also known as: CD103 IHC
Use
CD103 immunohistochemical (IHC) staining is a technical service (stain only) used to detect expression of the integrin subunit CD103 in tissue sections. CD103 expression can aid in diagnostic evaluation of certain lymphoid and epithelial lesions, particularly for identifying intraepithelial T‑lymphocytes and supporting evaluation in hematopathology (for example, hairy cell leukemia, marginal zone lymphomas), though interpretation requires correlation with clinical context and pathology review. The stain is offered as a technical component without pathologist interpretation (stain and return only).
Special Instructions
This is a stain‑and‑return (technical) service only, meaning only the technical IHC stain is performed; no interpretation is provided. Refer to ARUP’s Immunohistochemistry Stain Offerings brochure for ordering guidance. Ordering includes submission of either a tissue block or unstained positively charged slides using ARUP supply #47808 (tissue transport kit).
Limitations
Specimens not formalin‑fixed and paraffin‑embedded (eg, serum, blood, unprocessed tissue, or non‑positively charged slides) are unacceptable and will be rejected. Frozen specimens are unacceptable. Slides must not be oven‑baked if precut; storage and transport must maintain ambient or refrigerated temperature, with shipping cooled in summer. Interpretation is not included and must be pursued separately if desired. Performance is technical only; conclusions require integration with clinical/pathologic context.
New York Approved
Methodology
Immunoassay (IHC)
Biomarkers
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
Min: 2 slides
Container
tissue transport kit (ARUP supply #47808)
Collection Instructions
Transport tissue block or 5 unstained (3‑ to 5‑micron thick) positively charged slides; if sending precut slides, do not oven bake.
Storage Instructions
Room temperature or refrigerated; ship in cooled container during summer.
Causes for Rejection
Tissue or cells not processed into paraffin block; serum, blood, or body fluids; tissue not mounted on positively charged slides.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Indefinitely |
| Refrigerated | Indefinitely |
| Frozen | Unacceptable |