Chikungunya Antibodies, IgG and IgM
Also known as: CHIKPAN
Use
The Chikungunya Antibodies, IgG and IgM test is used to aid in the diagnosis of chikungunya viral infection during the acute phase of the disease, which is typically greater than 5 days after symptom onset. It is important for healthcare professionals to consider this test when the clinical presentation and travel history suggest a potential chikungunya infection or other arthropod-borne viruses that share similar symptomology.
Special Instructions
For optimal results, separate serum from cells as soon as possible or within 2 hours of collection. Use an ARUP standard transport tube for serum storage and transfer (minimum volume: 0.15 mL). Parallel testing is preferred, and convalescent specimens should be submitted within 30 days of the acute specimens. Clearly label specimens as 'acute' or 'convalescent.'
Limitations
The test primarily detects antibodies indicative of chikungunya virus infection, but false positives or negatives can occur. Care should be taken to evaluate results in conjunction with clinical presentation and other diagnostic tests. Hemolyzed, heat-inactivated, contaminated, or severely lipemic samples can lead to inaccurate results and are therefore unacceptable for testing.
Methodology
Immunoassay (ELISA)
Biomarkers
LOINC Codes
- 83067-9
- 83068-7
Result Turnaround Time
1-8 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.15 mL
Container
Serum separator tube (SST) or plain red or plasma (heparin, citrate, or EDTA)
Collection Instructions
Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP standard transport tube. Minimum volume: 0.15 mL.
Storage Instructions
Refrigerated
Causes for Rejection
Contaminated, heat-inactivated, hemolyzed, or severely lipemic specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 48 hours |
| Refrigerated | 2 weeks |
| Frozen | 1 year |
