Chlamydia Antibody Panel, IgG by IFA
Also known as: CHLAM G
Use
The Chlamydia Antibody Panel, IgG by IFA is used to differentiate between Chlamydophila species (C. psittaci, C. pneumoniae). It is important for identifying past exposure to Chlamydia species and differentiating reactions specific to C. pneumoniae, which will exhibit titers twofold or greater compared to C. trachomatis or C. psittaci. While this panel has limited value in diagnosing most oculogenital infections, IgG titers in recently infected individuals are typically greater than or equal to 1:512, indicating recent exposure.
Special Instructions
Parallel testing is preferred, and convalescent specimens must be received within 30 days from receipt of the acute specimens. Specimens should be marked plainly as 'acute' or 'convalescent.'
Limitations
The test contains both species- and genus-specific antigens, and serological cross-reactions may be observed in both acute and convalescent samples, particularly when titers are less than 1:128. The test does not include LGV strains of C. trachomatis, and its efficacy may be limited in diagnosing certain types of infections, such as oculogenital Chlamydia infections.
Methodology
Immunoassay (Indirect Fluorescent Antibody (IFA))
Biomarkers
LOINC Codes
- 6913-8
- 6919-5
- 6916-1
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.4 mL
Container
Plain red or serum separator tube
Collection Instructions
Separate serum from cells ASAP or within 2 hours of collection. Transfer to an ARUP standard transport tube.
Storage Instructions
Store refrigerated. Avoid repeated freeze/thaw cycles.
Causes for Rejection
Contaminated, hemolyzed, or hyperlipemic sera.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 48 hours |
| Refrigerated | 2 weeks |
| Frozen | 1 year |
