Chlamydia Antibody Panel, IgG & IgM by IFA
Also known as: V CHLM PAN
Use
This test is used to differentiate between Chlamydophila species (C. psittaci, C. pneumoniae) and to differentiate early IgM response to infection from persistent low-level titer. It is particularly useful for understanding serological responses and identifying past exposures. However, due to cross-reactivity, results need careful interpretation, especially as a C. pneumoniae-specific reaction may exhibit titers two-fold or greater compared to C. trachomatis or C. psittaci serology. This test has limited value in diagnosing most oculogenital chlamydial infections.
Special Instructions
Parallel testing is preferred, and convalescent specimens must be received within 30 days from receipt of acute specimens. Mark specimens plainly as 'acute' or 'convalescent.'
Limitations
Because of cross-reactivity, interpretation of results must consider potential serological overlaps between different Chlamydophila species. A specific reaction for C. pneumoniae could result in higher titer levels than those observed with other serological types like C. trachomatis or C. psittaci. The test is not FDA approved and does not include LGV strains of C. trachomatis, which limits its application to generalized Chlamydia detection rather than specific strain identification.
Methodology
Immunoassay (IFA)
Biomarkers
LOINC Codes
- 6914-6
- 6920-3
- 6917-9
- 6913-8
- 6919-5
- 6916-1
Result Turnaround Time
1-4 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.4 mL
Container
ARUP standard transport tube
Collection Instructions
Separate serum from cells ASAP or within 2 hours of collection. Transfer serum to an ARUP standard transport tube.
Storage Instructions
Refrigerated.
Causes for Rejection
Contaminated, hemolyzed, or hyperlipemic sera.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 48 hours |
| Refrigerated | 2 weeks |
| Frozen | 1 year (avoid repeated freeze/thaw cycles) |
