Chromosome Analysis, Leukemic Blood
Also known as: CHR LKB
Use
The Chromosome Analysis, Leukemic Blood test is used for the diagnosis, prognosis, and monitoring of hematopoietic neoplasms, particularly in cases where bone marrow is unavailable for cytogenetic studies. The test is pivotal in oncology studies, particularly for acute lymphoblastic leukemia (ALL), myeloproliferative neoplasms (MPNs), chronic lymphocytic leukemia (CLL), and myelodysplastic syndromes. It provides critical information by identifying chromosomal abnormalities that might influence treatment decisions and clinical outcomes.
Special Instructions
Not provided.
Limitations
The test involves culturing living cells, which means turnaround times are subject to variability. Frozen or clotted specimens are unacceptable as they compromise the integrity of cell cultures necessary for accurate chromosome analysis. As a laboratory-developed test (LDT), it has not been cleared or approved by the FDA, but is performed in a CLIA certified lab for clinical purposes.
New York Approved
Methodology
Chromosomal / Cytogenetics (G-Banding)
Biomarkers
Unknown CNV
Copy Number Region
LOINC Codes
- 62357-9 - Chrom analy overall interp-Imp
- 11526-1 - Pathology study
Result Turnaround Time
3-9 days
Related Documents
For more information, please review the documents below
Specimen
Whole Blood
Volume
5 mL
Minimum Volume
0.5 mL
Container
Green (sodium heparin) tube
Collection Instructions
Transport 5 mL whole blood.
Storage Instructions
Room temperature.
Causes for Rejection
Frozen specimens. Clotted specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 48 hours |
| Refrigerated | 48 hours |
| Frozen | Unacceptable |
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