Chronic Myelogenous Leukemia (CML) Profile: Chromosome Analysis and BCR-ABL, FISH
Also known as: BCR-ABL FISH and Chromosome Analysis, Chromosome Analysis and BCR-ABL FISH, Philadelphia Chromosome
Use
Confirm the diagnosis of chronic myelogenous leukemia; establish the chronic-phase karyotype for comparison with blast crisis alterations; monitor residual disease
Special Instructions
Include pertinent clinical diagnosis and previous cytogenetic studies on the test request form. Utilize sterile technique and Labcorp transport kits when possible.
Limitations
Molecular mutations or chromosomal alterations not targeted by the probe included in this profile will not be detected. This test is developed by Labcorp and has not been cleared or approved by the Food and Drug Administration.
Methodology
Chromosomal / Cytogenetics (FISH)
Biomarkers
LOINC Codes
- 62361-1
- 62360-3
- 51867-0
- 50398-7
- 31208-2
- 48672-0
- 11502-2
- 55199-4
- 62358-7
- 62356-1
- 62365-2
Result Turnaround Time
7-10 days
Related Documents
For more information, please review the documents below
Specimen
Bone Marrow
Volume
2 mL
Minimum Volume
1 mL
Container
Green-top (sodium heparin) tube
Collection Instructions
Utilize sterile technique and Labcorp transport kits when possible.
Storage Instructions
Transport to the testing laboratory at room temperature; use of a cool pack or a Labcorp transport kit is acceptable. Do not allow samples to overheat or freeze.
Causes for Rejection
Broken Vacutainer®; broken or stained slides; decalcified bone core; frozen specimen; quantity not sufficient for analysis
Other tests from different labs that may be relevant