Coccidioides Antibodies IgG by Immunoassay, CSF
Also known as: COCCIG CSF
Use
This test is used to screen for the presence of coccidioidal IgG antibodies in cerebrospinal fluid (CSF). It can help in detecting a current or recent infection of Coccidioides, a fungal pathogen that can lead to coccidioidomycosis, also known as Valley Fever. IgG antibodies typically appear by the third week of infection and may persist for several years. It’s important to use comprehensive diagnostic testing, as this test should not be relied upon as a standalone diagnostic measure.
Special Instructions
Parallel testing is preferred, and convalescent specimens should be received within 30 days from the receipt of acute specimens. Specimens must be marked plainly as acute or convalescent.
Limitations
This immunoassay should not be used as a standalone test but rather as part of a broader diagnostic panel that includes tests like complement fixation and immunodiffusion. Positive EIA results should be confirmed with these additional tests. The test result's reliability may be affected by specimen conditions such as contamination, hemolysis, or being lipemic. Also, other body fluids are not acceptable specimens.
FDA ApprovedNew York Approved
Methodology
Immunoassay (ELISA)
Biomarkers
LOINC Codes
- 16638-9
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Cerebrospinal Fluid
Volume
1 mL
Minimum Volume
0.3 mL
Container
ARUP Standard Transport Tube
Storage Instructions
Refrigerated
Causes for Rejection
Other body fluids. Contaminated, hemolyzed, xanthochromic, or severely lipemic specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 48 hours |
| Refrigerated | 2 weeks |
| Frozen | 1 year (avoid repeated freeze/thaw cycles) |