Cortisol, Inferior Vena Cava
Also known as: CORT IVC
Use
The Cortisol, Inferior Vena Cava test is used in the context of adrenal venous sampling procedures. It is significant in evaluating cortisol levels directly from the inferior vena cava, which can be particularly useful in assessing adrenal function and identifying hypercortisolism (Cushing's syndrome). This measurement can help differentiate between different causes of adrenal disorders and aid in the diagnostic process by providing precise cortisol levels from a location closely associated with adrenal outputs.
Special Instructions
Prior to sample collection, an adrenal venous sampling procedure must be conducted. This ensures the precision and specificity of the cortisol measurement from the adrenal region. Proper handling of the sample, such as allowing it to clot at room temperature and separating it from cells within 2 hours, is critical for accurate results.
Limitations
This test does not have an established reference interval, which may limit interpretive guidance for results. The lack of a reference interval means the results should be interpreted relative to other findings and clinical context. Additionally, care must be taken to avoid repeated freeze/thaw cycles as they can degrade the sample integrity. Stability of the sample is ensured only if the separation from cells and storage conditions are maintained as specified.
FDA ApprovedNew York Approved
Methodology
Immunoassay (ECLIA)
Biomarkers
LOINC Codes
- 2143-6
Result Turnaround Time
1 day
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.4 mL
Container
ARUP Standard Transport Tube
Collection Instructions
Allow specimen to clot completely at room temperature. Separate from cells ASAP or within 2 hours of collection.
Patient Preparation
Adrenal venous sampling procedure is required.
Storage Instructions
Refrigerated.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 24 hours |
| Refrigerated | 4 days |
| Frozen | 12 months (avoid repeated freeze/thaw cycles) |