Creatine, Serum or Plasma
Also known as: CRTN SP
Use
This test is used to monitor patients receiving creatine supplementation. Creatine levels can provide important information regarding creatine metabolism and transport in the body. Abnormal creatine levels may help in the assessment of mitochondrial diseases or inherited disorders of creatine metabolism. It is essential for evaluating conditions related to creatine deficiencies or abnormalities in its metabolism.
Special Instructions
For accurate assessment, it is necessary to separate serum or plasma from cells within 6 hours of collection and freeze immediately. This test is a Laboratory Developed Test (LDT) performed in a CLIA certified laboratory and is intended for clinical purposes. Additionally, for further evaluation of inherited disorders of creatine metabolism or transport, alternative or supplementary tests such as the Creatine Disorders Panel are recommended.
Limitations
The performance characteristics of this test have been determined by ARUP Laboratories and have not been cleared or approved by the FDA. The results are based solely on the specimen type and collection method outlined. Limitations include potential variability due to improper specimen handling, delayed separation of cells from serum/plasma, and multiple freeze/thaw cycles, which might impact test accuracy. Interpretation should consider these technical constraints.
Methodology
Mass Spectrometry
Biomarkers
LOINC Codes
- 15045-8
- 2148-5
Result Turnaround Time
2-9 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.2 mL
Container
ARUP standard transport tube
Collection Instructions
Separate from cells within 6 hours of collection. Transfer 1 mL serum or plasma to an ARUP standard transport tube and freeze immediately.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 6 hours |
| Refrigerated | 1 week |
| Frozen | 6 months |
