Estradiol, Free, by Dialysis and Mass Spectrometry
Also known as: ESDIOL FR
Use
This test is used to directly measure free estradiol levels and may be beneficial for assessing estradiol status in individuals with protein-binding abnormalities or those on hormonal contraception. It compares to other estrogen tests and is particularly useful for patient populations with specific conditions affecting hormone binding.
Special Instructions
This is a Laboratory Developed Test (LDT) carried out in a CLIA certified laboratory. The test employs Quantitative Equilibrium Dialysis/High Performance Liquid Chromatography-Tandem Mass Spectrometry methodologies.
Limitations
The test has yet to establish reference intervals for prepubertal females or cisgender males. Make sure to separate specimens from cells as soon as possible, preferably within two hours of collection. Avoid using ambient conditions for transport, and adhere to freezing requirements for prolonged storage.
New York Approved
Methodology
Mass Spectrometry
Biomarkers
LOINC Codes
- 2240-0
Result Turnaround Time
2-10 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
2 mL
Minimum Volume
1 mL
Container
Serum separator tube or green (sodium or lithium heparin), red top, plasma separator tube.
Collection Instructions
Separate from cells ASAP or within 2 hours of collection.
Storage Instructions
Transport frozen.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | unacceptable |
| Refrigerated | 1 week |
| Frozen | 6 months |