Gastric Pepsin A, Respiratory

Casandra

Casandra Test Code AR25691Version 1 (DRAFT)

Performing Lab

Lab ARUP LaboratoriesLab Test ID 3016813CPT Codes 82657, 83986, 84157

Gastric Pepsin A, Respiratory

Also known as: PEPSIN

Clinical Use

Order Test

Use

The Gastric Pepsin A, Respiratory test is utilized for detecting the presence of gastric pepsin A in respiratory specimens like bronchial wash, broncheoalveolar lavage (BAL), or tracheal aspirate. This test aids in the diagnosis of gastroesophageal reflux into the respiratory tract, which can lead to respiratory complications. Detection of pepsin A in respiratory samples is significant as it indicates gastric contents have reached the respiratory tract, which can be a marker for conditions such as laryngopharyngeal reflux.

Special Instructions

This test is not approved by the New York State Department of Health. Before collecting the specimen, submit a Non-Permitted Laboratory Request Form (NPL) to the NYDOH. Testing will be performed only if the NPL is approved. The test is performed by a non-ARUP laboratory, specifically the Nemours Childrens Health GI Laboratory. Specimens should be transferred immediately to an ARUP standard transport tube and frozen to maintain stability.

Limitations

The test may not be suitable for all patient populations as reference values are based on pediatric cases. Ambient or refrigerated specimens are unacceptable, and test results are contingent on the correct sample handling and processing. Interpretations are based on enzymatic assay results and may vary with changes in experimental conditions or sample integrity. Specimens should be tested separately for multiple test orders as the test is not performed at ARUP.

Test Details