Gastrin by Immunohistochemistry
Also known as: GASTRI IHC
Use
Immunohistochemical staining for gastrin, typically used to support diagnostic evaluation of gastrinoma or related neuroendocrine conditions such as Zollinger‑Ellison Syndrome. It serves as a technical (stain and return) service to local pathologists and clinicians to confirm gastrin expression in tissue specimens.
Special Instructions
This test is performed as a stain and return (technical) service only. Ordering is supported via electronic request or ARUP Immunohistochemistry Stain Form (#32978). The test is New York State Department of Health approved.
Limitations
Provides only immunohistochemical staining, without interpretive consultation provided by ARUP. Reliant on adequate fixation, embedding, and representation of target tissue. Depleted or non‑representative specimens are unacceptable and may lead to failure of stain or misinterpretation.
New York Approved
Methodology
Immunoassay (IHC)
Biomarkers
LOINC Codes
- 94736-6
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
5 unstained (3- to 5-micron thick sections) (min: 2 slides)
Container
tissue transport kit (ARUP supply #47808)
Collection Instructions
Formalin fix (10 percent neutral buffered formalin) and paraffin embed specimen (cells must be prepared into a cellblock). Transport tissue block or 5 unstained (3- to 5-micron sections), positively charged slides in tissue transport kit. If sending precut slides, do not oven bake.
Storage Instructions
Room temperature or refrigerated. Ship in cooled container during summer months.
Causes for Rejection
Non-representative tissue type; depleted specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Indefinitely |
| Refrigerated | Indefinitely |
| Frozen | Unacceptable |