Granzyme B by Immunohistochemistry
Also known as: GRANZB IHC
Use
Immunohistochemistry stain performed as a technical "stain and return" service to detect presence of Granzyme B antigen in tissue or cell specimens, aiding in diagnostic categorization (e.g., lymphoid or NK/T-cell lineage assessment).
Special Instructions
Not provided.
Limitations
Specimens must be formalin-fixed, paraffin-embedded tissue or cellblock; non-representative or depleted specimens are unacceptable. Frozen specimens unacceptable. Slides must be unbaked; if using precut slides, cannot be oven baked. Transported in proper kits. Service is technical only, without interpretation component at ARUP.
New York Approved
Methodology
Immunoassay (IHC)
Biomarkers
Granzyme B
Protein
LOINC Codes
- 94736-6 - Tissue block ID Spec
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
Not provided
Container
Tissue block or 5 unstained (3- to 5‑micron thick) positively charged slides in tissue transport kit (ARUP supply #47808)
Collection Instructions
Protect block or slides from excessive heat; do not oven bake precut slides; transport in ARUP tissue transport kit
Storage Instructions
Room temperature acceptable; refrigerated acceptable; ship in cooled container in summer
Causes for Rejection
Non‑representative tissue type; depleted specimens
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Indefinite |
| Refrigerated | Indefinite |
| Frozen | Unacceptable |
Other tests from different labs that may be relevant