Heat Shock Protein 70, IgG by Immunoblot
Also known as: HSP
Use
The presence of HSP70 IgG antibodies may be useful in predicting corticosteroid responsiveness in a subset of patients with autoimmune inner ear disease (AIED) characterized by idiopathic rapidly progressive sensorineural hearing loss (SNHL). HSP70 IgG antibodies are also associated with a number of autoimmune diseases and have also been reported in apparently healthy individuals. A negative result does not rule out response to treatment or to a diagnosis of AIED.
Special Instructions
Not recommended for evaluation of general hearing loss. The test is currently on delay as of 11/20/2025.
Limitations
This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes. A negative result does not rule out response to treatment or to a diagnosis of AIED.
New York Approved
Methodology
Immunoassay (Other)
Biomarkers
LOINC Codes
- 43597-4
Result Turnaround Time
1-8 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
0.5 mL
Minimum Volume
0.1 mL
Container
ARUP Standard Transport Tube
Collection Instructions
Collect using a Serum Separator Tube (SST) or Plain Red.
Storage Instructions
Refrigerated.
Causes for Rejection
Urine or plasma. Heat inactivated and contaminated specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 48 hours |
| Refrigerated | 2 weeks |
| Frozen | 1 year |