Hepatitis B Virus Surface Antigen with Reflex to Confirmation
Also known as: HBSAG
Use
The test helps diagnose acute or chronic Hepatitis B Virus infection by detecting the presence of the hepatitis B surface antigen (HBsAg) in the blood. It is commonly used in conjunction with other hepatitis markers for screening and monitoring. This test provides important information regarding the infection status of a patient, which is crucial for treatment decisions and for monitoring the effectiveness of therapy in infected individuals.
Special Instructions
The test is often ordered as part of the acute hepatitis panel, which includes HAV IgM, HBV core antibody IgM, HBV surface antigen, and HCV antibody. Specifically refer to 'Hepatitis Panel, Acute with Reflex to HBsAg Confirmation and Reflex to HCV by Quantitative NAAT (3002989)' for comprehensive analysis.
Limitations
This panel should not be used for blood donor screening, associated reentry protocols, nor for screening human cells, tissues, and cellular- and tissue-based products (HCT/P). False positives can occur in the screening; confirmatory testing helps clarify results when needed. If the initial screen is repeatedly reactive with an index value between 1.00 and 50.00, additional confirmation is performed.
FDA ApprovedNew York Approved
Methodology
Immunoassay (CLIA)
Biomarkers
LOINC Codes
- 5196-1
Result Turnaround Time
1 day
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
2 mL
Minimum Volume
1 mL
Container
ARUP standard transport tube
Collection Instructions
Separate serum from cells ASAP or within 2 hours of collection. Transfer serum to the transport tube.
Storage Instructions
Refrigerated.
Causes for Rejection
Heparinized plasma, specimens containing particulate material, heat-inactivated, severely hemolyzed, or lipemic specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Unacceptable |
| Refrigerated | 1 week |
| Frozen | Indefinitely |