Immunoglobulin G
Also known as: IGG
Use
The Immunoglobulin G (IgG) test is used to aid in the diagnosis or monitoring of IgG monoclonal gammopathies and IgG-related immune deficiencies. IgG is the most abundant type of antibody in the human serum and is critical in the body's immune response against bacterial and viral infections. Abnormal levels may indicate primary immunodeficiency diseases or other conditions affecting the immune system.
Special Instructions
This test requires the collection of a serum specimen using an SST (Serum Separator Tube). The serum should be separated from cells as soon as possible or within 2 hours of collection. After separation, the serum must be transferred to an ARUP Standard Transport Tube with a minimum volume of 0.5 mL. Specimens must be transported refrigerated to maintain specimen integrity.
Limitations
The test is not suitable for specimens that are grossly hemolyzed or lipemic as these conditions can interfere with the measurement of immunoglobulin levels. The stability of separated serum is 14 days when refrigerated and up to 6 months when frozen. However, ambient conditions are unacceptable for the stability of the serum.
FDA ApprovedNew York Approved
Methodology
Immunoassay (Immunoturbidimetry)
Biomarkers
LOINC Codes
- 2465-3
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.5 mL
Container
ARUP Standard Transport Tube
Collection Instructions
Separate serum from cells ASAP or within 2 hours of collection. Transfer to ARUP Standard Transport Tube.
Storage Instructions
Transport refrigerated.
Causes for Rejection
Grossly hemolyzed or lipemic specimens
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Unacceptable |
| Refrigerated | 14 days |
| Frozen | 6 months |