Immunoglobulin G, CSF Index
Also known as: IGG SYN
Use
The Immunoglobulin G, CSF Index test aids in the diagnosis and monitoring of patients with multiple sclerosis and other inflammatory diseases of the nervous system. It is used to assess the synthesis of immunoglobulin G within the central nervous system by comparing the levels of this protein in cerebrospinal fluid (CSF) and serum. This test provides important information for differentiating between multiple sclerosis and other neurological disorders.
Special Instructions
To ensure accurate result interpretation, it is recommended that both CSF and serum specimens be collected on the same day. If specimens are not collected within this specified timeframe, it is advised to exercise caution when interpreting the results.
Limitations
The test results may be influenced by the timing of specimen collection. Grossly bloody or hemolyzed specimens, as well as grossly lipemic specimens, are unacceptable and may result in rejection. Ambient specimen conditions are not acceptable; therefore, the stability of the samples should be maintained as per instructions for refrigeration or freezing.
New York Approved
Methodology
Immunoassay (Quantitative Immunoturbidimetry)
Biomarkers
LOINC Codes
- 1746-7
- 2465-3
- 2464-6
- 1751-7
- 1756-6
- 14116-8
- 2470-3
- 14117-6
- 48767-8
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Cerebrospinal Fluid
Volume
1 mL
Minimum Volume
0.5 mL
Container
ARUP standard transport tubes
Collection Instructions
Centrifuge and separate CSF to remove cellular material.
Storage Instructions
Refrigerated
Causes for Rejection
Grossly bloody or hemolyzed specimens, grossly lipemic specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Unacceptable |
| Refrigerated | 14 days |
| Frozen | 6 months |