Iron, Liver
Also known as: FE LIVER
Use
This test is useful in confirming hepatic iron overload, particularly in individuals with hemochromatosis and no common HFE mutations. It is designed to evaluate the iron concentration in liver tissue, assisting in diagnosing and monitoring disorders such as hemochromatosis, porphyria cutanea tarda, and cirrhotic liver diseases.
Special Instructions
Age is required on the test request form to calculate the iron index. The entire specimen submitted will be used up during the testing process.
Limitations
The Hepatic Iron Index is not calculated for patients less than 14 years old. Results may be affected by chelation therapies, chronic blood loss, or phlebotomy. Unacceptable conditions include specimens less than 0.25 mg dry weight or those stored or shipped in saline.
New York Approved
Methodology
Mass Spectrometry
Biomarkers
LOINC Codes
- 29638-4
- 15357-7
- 49061-5
- 11526-1
Result Turnaround Time
3-10 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (Fresh)
Volume
1 cm piece
Minimum Volume
0.25 mg dry weight
Container
Metal-free container, such as a royal blue (no additive)
Collection Instructions
Liver tissue obtained with an 18 gauge needle.
Storage Instructions
Refrigerated
Causes for Rejection
Specimens stored or shipped in saline; Specimens less than 0.25 mg dry weight
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Unacceptable |
| Refrigerated | 1 week |
| Frozen | Indefinitely |