Iron, Liver
Also known as: FE LIVER
Use
This test is useful in confirming hepatic iron overload, particularly in individuals with hemochromatosis and no common HFE mutations. It is designed to evaluate the iron concentration in liver tissue, assisting in diagnosing and monitoring disorders such as hemochromatosis, porphyria cutanea tarda, and cirrhotic liver diseases.
Special Instructions
Not provided.
Limitations
The Hepatic Iron Index is not calculated for patients less than 14 years old. Results may be affected by chelation therapies, chronic blood loss, or phlebotomy. Unacceptable conditions include specimens less than 0.25 mg dry weight or those stored or shipped in saline.
New York Approved
Methodology
Mass Spectrometry
Biomarkers
Hepatic Iron Concentration by Weight
AnalyteHepatic Iron Index
AnalyteTissue Weight
Analyte
LOINC Codes
- 29638-4 - Specimen wt Tiss Qn
- 15357-7 - Iron Tiss-mCnt
- 49061-5 - Hepatic iron index Liver-Rto
- 11526-1 - Pathology study
Result Turnaround Time
3-10 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (Fresh)
Volume
1 cm piece
Minimum Volume
0.25 mg dry weight
Container
Metal-free container, such as a royal blue (no additive)
Collection Instructions
Liver tissue obtained with an 18 gauge needle.
Storage Instructions
Refrigerated
Causes for Rejection
Specimens stored or shipped in saline; Specimens less than 0.25 mg dry weight
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Unacceptable |
| Refrigerated | 1 week |
| Frozen | Indefinitely |
Other tests from different labs that may be relevant