Japanese Encephalitis Virus Antibodies, IgG and IgM by ELISA
Also known as: JPN GM
Use
This test is used to detect the presence of Japanese encephalitis-related IgG and IgM antibodies in individuals showing evidence of acute encephalitis syndrome (AES) who have recently traveled to or resided in an endemic area in Asia or the western Pacific. The patient’s travel history is crucial for test interpretation, and the test is often used to differentiate from other arthropod-borne viruses with similar symptoms, such as dengue and West Nile viruses, based on clinical presentation and travel history.
Special Instructions
Patient's travel history is necessary to aid in test interpretation. Serum should be separated from cells as soon as possible or within 2 hours of collection. It should then be stored and transported refrigerated to preserve validity.
Limitations
The presence of JEV antibodies might either indicate a current, recent, or past infection. A positive IgG result might indicate an infection with a flavivirus within the Japanese encephalitis or dengue serogroups. IgG antibodies can be undetected in the early stage of JEV infection as their development can take several days to weeks. Therefore, testing for IgM-class antibodies is strongly recommended when IgG antibodies are undetectable. A low IgM antibody level may persist for more than 12 months post-infection.
New York Approved
Methodology
Immunoassay (ELISA)
Biomarkers
LOINC Codes
- 63562-3
- 7934-3
Result Turnaround Time
1-8 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
0.5 mL
Minimum Volume
0.15 mL
Container
Serum separator tube
Collection Instructions
Separate serum from cells ASAP or within 2 hours of collection.
Causes for Rejection
Contaminated or heat-inactivated specimens
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 48 hours |
| Refrigerated | 2 weeks |
| Frozen | 6 months |