Liver Fibrosis, Non-Alcoholic Fatty Liver Disease (Echosens)
Also known as: FIBRO NAFL
Use
The Echosens FibroMeter NAFLD profile serves as a surrogate marker of liver fibrosis in patients with non-alcoholic fatty liver disease (NAFLD). It calculates a patient score from 0 to 1, and correlates it with a fibrosis stage (Metavir F0-F4). It uses a proprietary algorithm that computes results from five blood markers, along with age and weight, to provide insights into liver fibrosis levels. This test is crucial for identifying the severity of fibrosis in NAFLD patients and should be interpreted in conjunction with clinical history.
Special Instructions
This test requires an automated platelet count performed on the EDTA whole blood sample at the client site. Include the platelet count with the patient test submission information. This test also requires the patient's weight. Patients must be fasting at the time of blood draw, as results may be inaccurate if not fasting. Calculations for the report are based on accurate data for age, weight, and platelet count.
Limitations
Results may be inaccurate in patients who are not fasting at the time of blood draw, or with other etiologies of chronic liver diseases such as viral hepatitis or alcoholic liver disease. Performance can also be affected by acute hepatitis, chronic inflammatory diseases other than liver, unstable glucose levels, unstable weight, or if the patient is under 18 years old or pregnant. This test has not been FDA cleared or approved.
New York Approved
Methodology
Automated Analyzer (Clinical Chemistry)
Biomarkers
LOINC Codes
- 26515-7
- 77616-1
- 1920-8
- 1742-6
- 2276-4
- 2345-7
- 29463-7
- 11526-1
- 48767-8
- 48794-2
Result Turnaround Time
1-5 days
Related Documents
For more information, please review the documents below
Specimen
Whole Blood
Volume
Not provided
Minimum Volume
Not provided
Container
Lavender (EDTA) or Pink (K2EDTA)
Collection Instructions
Collect Lavender (EDTA) or Pink (K2EDTA) for platelet count.
Patient Preparation
Patients must be fasting overnight before specimen collection.
Storage Instructions
Do not send the EDTA whole blood to ARUP.
Causes for Rejection
Hemolyzed specimens, all required specimens not received, no platelet count received, no weight received.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 24 hours |
| Refrigerated | 1 week |
| Frozen | 2 weeks |