Mumps Virus Antibody IgM, CSF
Use
The detection of antibodies to mumps in CSF may indicate central nervous system infection. However, consideration must be given to possible contamination by blood or transfer of serum antibodies across the blood-brain barrier. This test measures the presence of IgM antibodies specific to the mumps virus in CSF, which may indicate a current or recent infection. Persisting low levels of IgM antibodies may occur post-infection or after immunization.
Special Instructions
This test is not recommended for ordering. Additionally, this test is not approved for use in New York state; for specimens from New York clients, samples will be sent to a New York state-approved laboratory.
Limitations
The test results may be affected by contamination of CSF with blood or transfer of serum antibodies across the blood-brain barrier, which can lead to false positives. Low levels of IgM antibodies may persist for more than 12 months following infection or immunization, which can affect the interpretation of results.
Methodology
Immunoassay (ELISA)
Biomarkers
LOINC Codes
- 13267-0
Result Turnaround Time
1-5 days
Related Documents
For more information, please review the documents below
Specimen
Cerebrospinal Fluid
Volume
0.5 mL
Minimum Volume
0.2 mL
Container
ARUP standard transport tube
Storage Instructions
Refrigerated. Also acceptable: Frozen.
Causes for Rejection
Bacterially contaminated, heat-inactivated, hemolyzed, or xanthochromic specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 8 hours |
| Refrigerated | 2 weeks |
| Frozen | 1 year |