Myelin Oligodendrocyte Glycoprotein (MOG) Antibody, IgG by CBA-IFA With Reflex to Titer, Serum
Also known as: MOG SER
Use
This test aids in the diagnosis of central nervous system (CNS) demyelinating diseases or autoimmune encephalitis. The presence of myelin oligodendrocyte glycoprotein (MOG) antibody is associated with neuromyelitis optica spectrum disorders, including optic neuritis, transverse myelitis, brainstem encephalitis, and acute disseminated encephalomyelitis. The test may also be used to monitor antibody persistence or treatment response in individuals who are antibody positive.
Special Instructions
If the initial screen is positive, MOG Antibody Titer, IgG is performed in reflex. Additional charges apply for the reflex test.
Limitations
A negative test result does not rule out a diagnosis of CNS demyelinating disease. Persistence of antibody positivity may be associated with a relapsing course. Results should be interpreted in correlation with the patient's clinical history and other laboratory findings.
New York Approved
Methodology
Cell-based / Cytometry (Other)
Biomarkers
LOINC Codes
- 91545-4
Result Turnaround Time
1-6 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.15 mL
Container
ARUP standard transport tube
Collection Instructions
Collect in Serum separator tube (SST) or plain red.
Storage Instructions
Refrigerated
Causes for Rejection
Hemolyzed, contaminated, or severely lipemic specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 48 hours |
| Refrigerated | 2 weeks |
| Frozen | 1 month |