N-Telopeptide, Cross-Linked, Serum
Also known as: NTX SERUM
Use
The N-Telopeptide, Cross-Linked, Serum test measures the concentration of cross-linked N-telopeptides of type I collagen, which is a marker of bone resorption. It is primarily used for monitoring bone turnover in patients with osteoporosis. The test provides insight into the effectiveness of osteoporosis treatment by tracking changes in bone turnover markers, which can guide therapeutic decisions.
Special Instructions
The test requires a serum sample collected in a plain red or serum separator tube. The sample should be transferred to an ARUP Standard Transport Tube and frozen for transport. It is important to follow the specified collection and handling procedures to ensure the accuracy of test results.
Limitations
The test may not be suitable for determining bone turnover rates in patients with disorders affecting collagen synthesis or degradation. Severely hemolyzed specimens are not acceptable for testing. Results must be interpreted in conjunction with clinical findings and other laboratory test results. Additionally, the reference intervals provided may not apply to all patient populations, and individual variability in biomarker levels may influence measurements.
FDA ApprovedNew York Approved
Methodology
Immunoassay (ELISA)
Biomarkers
LOINC Codes
- 21215-9
Result Turnaround Time
1-4 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
0.5 mL
Minimum Volume
0.2 mL
Container
ARUP Standard Transport Tube
Collection Instructions
Collect in plain red or serum separator tube. Transfer 0.5 mL serum to an ARUP Standard Transport Tube.
Storage Instructions
Frozen
Causes for Rejection
Severely hemolyzed specimens
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 5 hours |
| Refrigerated | 24 hours |
| Frozen | 6 months |