Use

This test is used to detect and monitor nicotine and cotinine in serum or plasma, which can be useful when a valid urine specimen cannot be obtained, such as in cases of anuria or dialysis. It evaluates recent use of nicotine-containing products, although it cannot definitively discriminate between passive and active exposure. It is useful for smoking cessation programs or compliance testing, as the absence of expected drug(s) or drug metabolite(s) could indicate noncompliance or other issues.