P40 by Immunohistochemistry
Also known as: P40 IHC
Use
The P40 by Immunohistochemistry test is used for the detection of the P40 protein, which is a marker useful in certain clinical and pathological evaluations. The staining pattern and intensity can help in differentiating squamous cell carcinomas from other types of tumors. The test is performed in a CLIA certified laboratory and is intended for clinical purposes to aid in diagnosis.
Special Instructions
The test is offered as a technical service which means that it provides stain and return only for the tissue specimens. Formalin-fixed and paraffin-embedded specimens are required, with specific instructions on how to handle and transport them to ensure their stability and integrity.
Limitations
This test has not been cleared or approved by the US Food and Drug Administration. It is developed and validated by ARUP Laboratories as a laboratory-developed test (LDT). The test results should be interpreted within the context of the clinical picture and other diagnostic findings. Non-representative tissue types and depleted specimens may lead to rejection of samples.
New York Approved
Methodology
Immunoassay (IHC)
Biomarkers
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
2 slides
Container
Tissue transport kit
Collection Instructions
Formalin fix (10 percent neutral buffered formalin) and paraffin embed specimen. Transport tissue block or 5 unstained (3- to 5-micron thick sections), positively charged slides.
Storage Instructions
Room temperature; acceptable refrigerated. Ship in cooled container during summer.
Causes for Rejection
Specimens submitted with non-representative tissue type. Depleted specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Indefinitely |
| Refrigerated | Indefinitely |
| Frozen | Unacceptable |