Prostate Specific Antigen, Complexed

Casandra

Casandra Test Code AR02180Version 1 (DRAFT)

Performing Lab

Lab ARUP LaboratoriesLab Test ID 2002930CPT Code 84152

Prostate Specific Antigen, Complexed

Also known as: PSA COMP

Clinical Use

Order Test

Use

This test is used as an aid in the detection of prostate cancer in men age 50 and older when used in conjunction with a digital rectal exam. It is also utilized for managing and monitoring prostate cancer patients. The test helps in differentiating between prostate cancer and other prostatic conditions, as its levels are usually not elevated in healthy individuals or non-prostatic carcinoma cases. However, elevated levels can occur in benign prostatic hyperplasia or inflammatory conditions of the prostate. Careful interpretation is required for patients under treatment with antiandrogens and LHRH agonists and antagonists, as they may show reduced levels of cPSA.

Special Instructions

This test is approved by the New York State Department of Health. It uses the Siemens' Atellica® IM cPSA methodology, which is FDA approved. Prostatic biopsy remains a requirement for definitive cancer diagnosis, and results from this assay should not be used interchangeably with those from different methods.

Limitations

Results from different assay methods or kits cannot be used interchangeably. cPSA is not elevated in healthy men or with non-prostatic carcinoma, and results may be affected by benign prostatic hyperplasia or inflammatory prostate conditions. Prostate cancer patients under treatment with antiandrogens and LHRH agonists/antagonists may have reduced levels of cPSA, requiring careful interpretation.

Test Details

FDA Approved