Prostate-Specific Kallikrein, 4Kscore
Also known as: 4KSCORE
Use
The Prostate-Specific Kallikrein, 4Kscore test is used to stratify the risk of aggressive prostate cancer in men aged 45 or older with elevated prostate-specific antigen (PSA) levels, for whom biopsy is under consideration. This test helps in decision-making by estimating the probability of aggressive prostate cancer, thus aiding in the management of prostate health.
Special Instructions
Not provided.
Limitations
The test has limitations in scenarios where recent prostate procedures or pharmacological interventions could influence PSA levels, potentially leading to inaccurate risk assessments. The test isn't suitable for individuals with a history of prostate cancer as the prior diagnosis would invalidate the stratification outcome expected by this test.
New York Approved
Methodology
Immunoassay (ECLIA)
Biomarkers
LOINC Codes
- 10205-3 - Phys find Rectum
- 104720-8 - Clinical indication
- 19146-0 - Ref Lab Test Results
- 66117-3 - Prostate Path Bx report
- 83112-3 - PSA SerPl IA-mCnc
- 66117-3 - Prostate Path Bx report
- 10205-3 - Phys find Rectum
- 19146-0 - Ref Lab Test Results
- 83112-3 - PSA SerPl IA-mCnc
- 104720-8 - Clinical indication
Result Turnaround Time
5-10 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
4 mL
Minimum Volume
3 mL
Container
ARUP standard transport tube
Collection Instructions
Transfer serum from an SST (serum separator tube) to an ARUP standard transport tube. The test is not performed at ARUP; ensure separate specimens if multiple tests are ordered.
Storage Instructions
Frozen
Causes for Rejection
Frozen serum separator tubes (SST).
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Unacceptable |
| Refrigerated | 72 hours |
| Frozen | 1 month |
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