Rickettsia typhi (Typhus Fever) Antibodies, IgG & IgM by IFA
Also known as: TYPHU G/M
Use
This test is used to confirm the presence of Rickettsia typhi by detecting specific IgG and IgM antibodies using the Indirect Fluorescent Antibody (IFA) method. It is often used in cases where typhus fever infection is suspected. A comparison between acute and convalescent-phase serology is necessary to identify recent infections, typically by noting a significant change in antibody titers.
Special Instructions
Specimens must be marked as "acute" or "convalescent". Convalescent specimens should be received within 30 days from receipt of the acute specimens for accurate comparison.
Limitations
A single antibody titer result can be misleading; interpretation requires a significant change in titer in properly timed specimens. The test may yield false negatives if specimens are improperly timed or if cross-reactivity with other Rickettsia species occurs.
New York Approved
Methodology
Immunoassay (IFA)
Biomarkers
LOINC Codes
- 5324-9
- 5325-6
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.4 mL
Container
Serum Separator Tube (SST), transferred to an ARUP standard transport tube
Collection Instructions
Separate from cells ASAP or within 2 hours of collection.
Storage Instructions
Refrigerated transport. Ambient stability for 48 hours, refrigerated stability for 2 weeks, frozen stability for 1 year.
Causes for Rejection
Contaminated, hemolyzed, or severely lipemic specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 48 hours |
| Refrigerated | 2 weeks |
| Frozen | 1 year |