Streptococcus pneumoniae Antigen, CSF

Casandra

Casandra Test Code AR30199Version 1 (DRAFT)

Performing Lab

Lab ARUP LaboratoriesLab Test ID 0061162CPT Code 87899

Streptococcus pneumoniae Antigen, CSF

Also known as: SPN CSF

Clinical Use

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Use

This test aids in the diagnosis of pneumococcal meningitis by detecting the presence of Streptococcus pneumoniae antigen in the cerebrospinal fluid (CSF). It is used primarily to identify cases of pneumococcal meningitis, a severe infection of the membranes surrounding the brain and spinal cord. This test is particularly useful for patients suspected of having pneumococcal meningitis as it provides a rapid diagnostic tool to confirm the presence of Streptococcus pneumoniae antigens in the central nervous system.

Special Instructions

Patients who have recently received the S. pneumoniae vaccines may show positive test results within 48 hours post-vaccination. It is advisable to avoid antigen detection testing within this window and wait for at least 5 days after vaccination. When ordering Streptococcus pneumoniae antigen detection in CSF from specific hospitals, a CSF culture test is automatically added unless otherwise requested, which may incur additional charges.

Limitations

False-positive results may occur due to cross-reactivity with other members of the S. mitis group. Therefore, clinical correlation is recommended to interpret the results accurately. The test should not be used solely as a definitive diagnostic tool without supporting clinical information. Bacterial antigen detection tests performed on CSF should be confirmed with a culture to ensure accurate diagnosis and rule out false positives or negatives.

Test Details

FDA Approved