Thyroxine, Total T4

Also known as: T4 TOTAL

Clinical Use

Use

Thyroxine, Total T4 measurement is critical for assessing thyroid function and diagnosing thyroid disorders. It provides essential information about the thyroid hormone levels, which are crucial for metabolic processes, growth, and development. This test helps identify both hyperthyroidism and hypothyroidism, adjusting treatment and monitoring responses to therapy. It is not recommended for routine screening but is valuable in evaluating existing thyroid dysfunction and guiding endocrinological healthcare decisions.

Special Instructions

Not provided.

Limitations

This test cannot be used as a standalone diagnostic tool for thyroid disorders. Variability can occur due to factors such as protein-binding or medication interference. Total T4 levels can be affected by conditions unrelated to thyroid function, such as pregnancy, oral contraceptives, and systemic illnesses. Results should be interpreted in conjunction with other thyroid function tests, patient history, and clinical findings to ensure accurate diagnosis and management.

Test Details

New York Approved

Methodology

Immunoassay (ECLIA)

Biomarkers

LOINC Codes

Result Codes

3026-2 - T4 SerPl-mCnc

Result Turnaround Time

1 day

Specimen

Serum

Volume

1 mL

Minimum Volume

0.5 mL

Container

Serum separator tube or green (lithium heparin); also acceptable: lavender (K2EDTA or K3EDTA), or pink (K2EDTA)

Collection Instructions

Allow specimen to clot completely at room temperature. Separate serum or plasma from cells ASAP or within 2 hours of collection. Transfer to an ARUP standard transport tube.