Treponema pallidum (VDRL), Cerebrospinal Fluid with Reflex to Titer
Also known as: VDRL CSF
Use
The test is the preferred diagnostic assay for cerebrospinal fluid (CSF) specimens in suspected cases of neurosyphilis, allowing healthcare providers to diagnose this serious neurological condition. The reflex to titer provides additional information to gauge the extent of infection if the initial VDRL result is positive.
Special Instructions
If the VDRL test result is weakly reactive or reactive, a titer will be added to quantify the extent of infection, which may incur additional charges. It is important to collect an adequate volume of CSF and ensure it is not contaminated or improperly stored to avoid rejection.
Limitations
The test is specifically designed for cerebrospinal fluid specimens and may not be suitable for other types of body fluids. Contaminated, hemolyzed, xanthochromic, or severely lipemic specimens are unacceptable, potentially leading to inaccurate results or rejection of the sample. Also, repeated freeze/thaw cycles can affect the specimen integrity.
New York Approved
Methodology
Other
Biomarkers
LOINC Codes
- 5290-2
Result Turnaround Time
1-4 days
Related Documents
For more information, please review the documents below
Specimen
Cerebrospinal Fluid
Volume
0.5 mL
Minimum Volume
0.4 mL
Container
ARUP standard transport tube
Storage Instructions
Refrigerated
Causes for Rejection
Other body fluids. Contaminated, hemolyzed, xanthochromic, or severely lipemic specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 48 hours |
| Refrigerated | 2 weeks |
| Frozen | 1 year |