West Nile Virus Antibodies, IgG and IgM by ELISA, CSF
Also known as: WNILE CSF
Use
This test is primarily used to detect West Nile virus-specific IgG and IgM antibodies in cerebrospinal fluid (CSF) to help diagnose central nervous system infections suspected to be caused by the West Nile virus. Due to cross-reactivity with other Flaviviridae family members such as the St. Louis encephalitis virus, specific serologic testing for these species may be considered in the differential diagnosis. It is important to correlate the test results with clinical history and other data.
Special Instructions
Specimens from New York clients will be sent out to a New York state-approved laboratory as this test is not approved for use in New York. It is recommended that serum testing for the same analyte be performed to aid in interpreting the CSF test result when blood contamination is present in the CSF.
Limitations
This test should not be used solely for quantitative purposes and should always be correlated with clinical history and other data due to cross-reactivity with other Flaviviridae family viruses. Blood contamination can lead to false positives or false negatives.
Methodology
Immunoassay (ELISA)
Biomarkers
LOINC Codes
- 39572-3
- 39573-1
Result Turnaround Time
1-6 days
Related Documents
For more information, please review the documents below
Specimen
Cerebrospinal Fluid
Volume
2 mL
Minimum Volume
0.3 mL
Container
ARUP Standard Transport Tube
Causes for Rejection
Bacterially contaminated, heat-inactivated, hemolyzed, or xanthochromic specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 8 hours |
| Refrigerated | 2 weeks |
| Frozen | 1 year |