West Nile Virus Antibody, IgG by ELISA, CSF
Also known as: WNIL IGG
Use
This test is intended to be used as a semi-quantitative means of detecting West Nile virus-specific IgG in CSF specimens in which there is a clinical suspicion of West Nile virus infection. The detection of antibodies to West Nile virus in cerebrospinal fluid may indicate central nervous system infection. However, consideration must be given to possible contamination by blood or transfer of serum antibodies across the blood-brain barrier. Results should not be used solely for quantitative purposes, nor should they be interpreted without correlation to clinical history or other data.
Special Instructions
New York State Clients: Specimens from New York clients will be sent out to a New York state-approved laboratory. NYSDOH will only approve West Nile Virus Antibody testing when performed as an IgG, IgM panel.
Limitations
Because other members of the Flaviviridae family, such as St. Louis encephalitis virus, show extensive cross-reactivity with West Nile virus, serologic testing specific for these species should be considered. This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. It is performed in a CLIA certified laboratory and intended for clinical purposes.
Methodology
Immunoassay (ELISA)
Biomarkers
LOINC Codes
- 39572-3
Result Turnaround Time
1-6 days
Related Documents
For more information, please review the documents below
Specimen
Cerebrospinal Fluid
Volume
2 mL
Minimum Volume
0.3 mL
Container
ARUP Standard Transport Tube
Collection Instructions
Transfer 2 mL CSF to an ARUP Standard Transport Tube.
Storage Instructions
Refrigerated.
Causes for Rejection
Bacterially contaminated, heat-inactivated, hemolyzed, or xanthochromic specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 8 hours |
| Refrigerated | 2 weeks |
| Frozen | 1 year (avoid repeated freeze/thaw cycles) |