Dual Genome Panel by Massively Parallel Sequencing
Use
The Dual Genome Panel is a comprehensive genetic test designed to evaluate 164 nuclear genes and 37 mitochondrial genes linked to mitochondrial disorders. These conditions can be difficult to diagnose due to the interplay of various symptoms that may affect multiple organ systems. Common symptoms include muscle weakness, developmental delay, and complications involving the heart, liver, and kidneys. Accurate diagnosis is crucial as it guides management and treatment strategies. Furthermore, individuals with suspected mitochondrial disorders can benefit from confirmation of diagnosis, facilitating appropriate care and monitoring.
Special Instructions
Benign variants from dbSNP and variants of unknown clinical significance are not included in the report. If required, these can be requested separately. The understanding of gene relationships may evolve over time, so this report is based on the current genetic insights.
Limitations
The interpretation of findings may change over time with advancements in knowledge regarding these genes. Diagnostic errors can occur due to sample mix-ups, genetic variants hindering proper analysis, incorrect biological parentage assignment, or other unforeseen discrepancies. Please consult with a genetic counselor at Baylor Genetics if there is suspicion of errors affecting your analysis.
New York Approved
Methodology
NGS (Targeted)
Biomarkers
Result Turnaround Time
28 days
Related Documents
For more information, please review the documents below
Specimen
Whole Blood (Fresh)
Volume
3-5 cc
Minimum Volume
3 cc
Container
EDTA (purple-top) tube
Collection Instructions
Draw blood in an EDTA (purple-top) tube(s) and send 3-5 cc (Adults/Children) and 3 cc (Infant<2yrs).
Storage Instructions
Ship at room temperature in an insulated container by overnight courier. Do not heat or freeze.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 72 hours |