17-OH Progesterone/Creatinine Ratio, 24-Hour Urine

Also known as: 17-OHP Urine

Clinical Use

Use

17-Hydroxyprogesterone (17-OHP) in urine is greatly elevated in patients with polycystic ovarian disease and in patients with idiopathic hirsutism.

Special Instructions

Not provided.

Limitations

This test was developed and its performance characteristics determined by Labcorp. It has not been cleared or approved by the Food and Drug Administration (FDA). Specimens with no preservative or a pH not ≤3 may be rejected. Proper specimen collection and handling are crucial for accurate results.

Test Details

Methodology

Mass Spectrometry

Biomarkers

17-OH Progesterone

Analyte

17-OH Progesterone, Urine

Concentration / Level • Quantitative (Continuous) (e.g., copies/mL, % expression)

Creatinine

Analyte

Creatinine, Random U

Concentration / Level • Quantitative (Continuous) (e.g., copies/mL, % expression)

LOINC Codes

Order Codes

1670-9 - 17OHP Ur-mCnc
2161-8 - Creat Ur-mCnc
63042-6 - 17OHP/Creat Ur
9616-4 - 17OHP 24h Ur-mRate

Result Turnaround Time

3-6 days

Specimen

Urine

Volume

30 mL aliquot

Minimum Volume

4 mL aliquot

Container

Plastic urine container with 30 mL 6N HCl preservative

Collection Instructions

Instruct the patient to void at 8 a.m. and discard the specimen. Preservative must be added to the container prior to the start of collection. Then collect all urine including the final specimen voided at the end of the 24-hour collection period (i.e., 8 a.m. the next morning). Measure and record total urine volume on the request form. Label container with patient's name, date and time collection started, and date and time collection finished. Keep collection on ice. Remove 20 mL aliquot. pH should be ≤3.