17-Hydroxycorticosteroids, Urine
Also known as: HYD CORT
Use
The 17-Hydroxycorticosteroids, Urine test measures the level of 17-Hydroxycorticosteroids in urine. It is used to assess adrenal gland function and to diagnose disorders related to corticosteroid production. Elevated levels can be indicative of disorders such as Cushing's syndrome, adrenal hyperplasia, or adrenal tumors. This test is often part of the evaluation of patients with suspected adrenal insufficiency or hypercortisolism.
Special Instructions
Patient should collect a 24-hour urine sample. During collection, the sample should be refrigerated. Specimens should be frozen within 15 minutes if collected randomly, with no need for preservatives. For 24-hour collections, total volume, collection time, and pH must be recorded on the transport tube and test request form. Ensure sample pH is adjusted to 5.0-7.0 using boric acid. Specimens that have been preserved with alkali preservatives like NaOH are not acceptable.
Limitations
Results should be interpreted with caution as factors like improper collection, incorrect pH adjustment, and inappropriate storage conditions may affect test outcomes. The test may not be suitable for patients with significant deviations in urine collection volume or duration from the standard 24-hour period, as this can impact the calculation of analyte levels per day. The lack of a reference interval for reported values necessitates careful interpretation by clinicians familiar with the patient's clinical condition and history.
New York Approved
Methodology
Automated Analyzer (Clinical Chemistry)
Biomarkers
LOINC Codes
- 19153-6
- 21036-9
- 2162-6
- 30211-7
- 35674-1
- 41404-5
Result Turnaround Time
3-7 days
Related Documents
For more information, please review the documents below
Specimen
Urine
Volume
12 mL aliquot from 24-hour collection
Minimum Volume
Not provided
Container
ARUP Standard Transport Tubes
Collection Instructions
Collect 24-hour urine sample, refrigerate during collection. For random specimens, freeze within 15 minutes without preservative. Adjust pH with boric acid to 5.0-7.0, and record details on the transport tube and test request form.
Storage Instructions
Store and transport frozen.
Causes for Rejection
Specimens preserved with alkali preservatives like NaOH.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 4 hours (with preservative) |
| Refrigerated | 1 week (with preservative) |
| Frozen | 1 month |
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