17-OH Progesterone, LC/MS, Seven Specimens
Use
This test is used to measure the level of 17-hydroxyprogesterone (17-OH Progesterone) in the blood. It is typically used in the evaluation of patients with suspected congenital adrenal hyperplasia (CAH), a genetic disorder affecting adrenal gland function that can cause abnormal hormone levels and affect sexual development. Monitoring 17-OH Progesterone levels is crucial for diagnosing and managing CAH, particularly in assessing the need for specific treatments such as glucocorticoid replacement therapy.
Special Instructions
This panel is a series panel requiring multiple tubes to be drawn at multiple time points. It is used to collect an initial tube (baseline) and then administer a drug (pill or shot) or other treatment (such as glucola), followed by collecting additional tubes. If no treatment is administered after the first sample draw, this panel should not be used. Collection should not proceed until the clinician is contacted to confirm the reason for ordering the series.
Limitations
The test results must be evaluated with caution in the context of the patient's clinical presentation and other diagnostic tests. The presence of cross-reactivity with similar steroids may influence results. False results may occur if the samples are not collected according to the specified protocol, such as incorrect timing of sample collections. Possible technical variations in LC/MS methods might also impact outcomes, and confirmatory testing or alternative methods may be necessary for ambiguous results.
Methodology
Mass Spectrometry
Biomarkers
LOINC Codes
- 27996-8
- 46963-5
- 51680-7
- 12716-7
- 12717-5
- 12718-3
- 12719-1
- 51679-9
Result Turnaround Time
3-7 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
Not provided
Minimum Volume
Not provided
Collection Instructions
Refer to the Endocrine Appendix of the LabCorp Directory of Services for instructions on multiple specimen testing.