Acetylcholinesterase (AChE), Amniotic Fluid With Reflex to Fetal Hemoglobin (Hb F)
Also known as: AChE, Amniotic Fluid With Reflex to Hb F
Use
Analysis of midtrimester amniotic fluid for detection of open neural tube defects and ventral wall defects
Special Instructions
The patient's gestational age must be at least 13 weeks for accurate AChE detection. Optimal gestational age is between 14 to 18 weeks. It's essential to include the gestational age derived from ultrasound and/or last menstrual period (LMP) on the request form to ensure accuracy in test results.
Limitations
This test was developed and its performance characteristics determined by Labcorp and has not been cleared or approved by the Food and Drug Administration. Contamination with maternal or fetal blood, even in minimal amounts, can lead to false-positive results, complicating the analysis and interpretation of AChE and Hb F levels in amniotic fluid.
Methodology
Other
Biomarkers
LOINC Codes
- 510354
- 30106-9
- 76479-5
Result Turnaround Time
4-12 days
Related Documents
For more information, please review the documents below
Specimen
Amniotic Fluid
Volume
3 mL
Minimum Volume
Not provided
Container
Sterile plastic conical tube; do not use urine containers or tubes with rubber stoppers. Rubber is toxic to amniocytes.
Collection Instructions
Avoid contamination of amniotic fluid with maternal or fetal blood. Amniotic fluid should be collected by the attending physician.
Patient Preparation
The patient should have undergone ultrasound studies to verify fetal viability, detect multiple gestations, confirm gestational age, localize the placenta, and detect fetal and uterine pathology.
Storage Instructions
Ship and maintain specimen at room temperature.
Causes for Rejection
Specimen found not to be amniotic fluid; gross contamination with blood; quantity not sufficient for analysis