Amphetamines Screen With Reflex Confirmation, Whole Blood

Casandra

Casandra Test Code LC99060Version 1 (DRAFT)

Performing Lab

Lab LabcorpLab Test ID 700876CPT Code 80307

Amphetamines Screen With Reflex Confirmation, Whole Blood

Clinical Use

Use

The Amphetamines Screen with Reflex Confirmation is designed to detect the presence of amphetamines and related compounds in whole blood. Initial testing employs immunoassay techniques with a threshold sensitivity of 50 ng/mL to screen for the presence of amphetamines. Samples that test positive in this presumptive screen are confirmed using definitive chromatography mass spectrometry techniques (GC/MS or LC/MS-MS) to ensure accuracy and specificity. This test is useful for confirming intoxication or unlawful consumption of amphetamines in various contexts such as employment screenings or clinical assessments.

Special Instructions

The test involves an initial immunoassay screening followed by reflex confirmation for presumptive positives using mass spectrometry techniques. It is important to adhere to proper storage conditions; specimens should be stored at room temperature if tested within three days of collection or refrigerated/freezed if stored for longer periods. The submission should be made using the appropriate container type as listed in specimen requirements.

Limitations

While the test is sensitive and specific when confirmation by GC/MS or LC/MS-MS is performed, it has not been cleared or approved by the FDA. Potential cross-reactivity or interference from other drugs or substances may lead to false positives or negatives, particularly in the initial immunoassay screen. Therefore, it should be used as part of a broader assessment when determining amphetamine use. Stability conditions also dictate sample handling to ensure accuracy.

Test Details