Antiribosomal P Antibodies
Use
Ribosomal P antibodies are found in 10% to 20% of patients with systemic lupus erythematosus (SLE) and are purported to be associated with lupus psychosis.
Special Instructions
Specimens should be collected in a red-top or gel-barrier tube and sent to the laboratory as soon as possible. It is crucial to avoid hemolysis, lipemia, or gross bacterial contamination, as these conditions may cause specimen rejection.
Limitations
The presence of antiribosomal P antibodies is not exclusively indicative of systemic lupus erythematosus (SLE) and may be found in a smaller percentage of patients without this condition. Moreover, positive results should be interpreted cautiously in the context of clinical findings and other laboratory tests due to the potential for false positives or varying antibody levels based on disease activity.
Methodology
Cell-based / Cytometry (Flow Cytometry)
Biomarkers
LOINC Codes
- 13636-6
- 13636-6
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.3 mL
Container
Red-top tube or gel-barrier tube
Storage Instructions
Room temperature
Causes for Rejection
Hemolysis; lipemia; gross bacterial contamination; icterus
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 14 days |
| Refrigerated | 14 days |
| Frozen | 14 days |