Bacterial Vaginosis (Sialidase), Chlamydia trachomatis, Neisseria gonorrhoeae, Trichomonas vaginalis, NAA, Vaginal Yeast Culture
Also known as: BV (Sialidase), Ct/Ng/Tv (NAA), Vaginal Yeast (Culture)
Use
BV (sialidase) activity: Enzyme activity test for use in the detection of vaginal fluid specimens for sialidase activity, an enzyme produced by bacteria associated with bacterial vaginitis, including Bacteroides spp, Prevotella spp, and Mobiluncus spp, and some G vaginalis. In a recent study, Bradshaw et al demonstrated the test to be 88% sensitive and 95% specific.
Special Instructions
Avoid collecting specimens from the cervix as it can increase risks for obstetric patients and may not reflect the true vaginal sialidase activity. Patients should not use vaginal creams, douches, spermicides or lubricants within 72 hours prior to specimen collection to avoid inaccurate results. Swabs should be placed immediately in provided transport tubes and stored appropriately.
Limitations
Collecting from the cervix might produce misleading results due to naturally higher sialidase activity. False negatives are possible if samples are insufficient or collected from individuals undergoing antimicrobial treatment. Specimen rejection could occur if transport instructions are not followed or if submitted with disallowed devices.
Methodology
Other
Biomarkers
LOINC Codes
- 41477-1
- 18483-8
- 43304-5
- 43305-2
- 46154-1
Result Turnaround Time
3-5 days
Related Documents
For more information, please review the documents below
Specimen
Other
Volume
Multiple swab specimens
Minimum Volume
Not provided
Container
Copan double swab in Amies liquid medium and Aptima® unisex swab transport
Collection Instructions
Using transport swabs provided, collect vaginal fluid sample by contacting the lower one-third of the vaginal wall, rotating for 10 to 20 seconds to absorb fluid. Immediately place the swabs into the transport tubes. For the Aptima® swab, carefully break the swab shaft against the side of the tube. Tightly screw on the cap.
Patient Preparation
Do not use vaginal creams, ointments, douches, spermicides, lubricants, and feminine sprays within 72 hours of the test.
Storage Instructions
Maintain specimen at room temperature or refrigerate (2°C to 30°C).
Causes for Rejection
Unlabeled specimens, discrepancy between specimen label and the test request form, use of disallowed swabs or transport media, and specimens from patients under 16 years of age.