Special Instructions

The condition may affect approximately 1% of the US population but is often underdiagnosed. Strict avoidance of gluten in the diet can control disease activity, leading to the disappearance of serum markers over time. Consider clinical guidelines for the diagnosis and treatment of celiac disease in children as recommended by the North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition.

Limitations

The test might not detect all cases of celiac disease, as it primarily identifies specific antibodies. False negatives may occur, particularly if the patient has already eliminated gluten from their diet or possesses selective IgA deficiency. Consider results in conjunction with clinical findings and consider additional tests or biopsies if necessary. The presence of antibodies in the serum will decline with the exclusion of gluten from the diet, potentially impacting monitoring results. There may be variability in results depending on individual patient factors, and additional confirmatory tests are sometimes required to conclusively diagnose the condition.

Biomarkers

LOINC Codes

Result Turnaround Time

Related Documents

Stability Requirements