Celiac Antibodies Profile tTG IgA, tTG IgG, DGP IgA, DGP IgG, EMA IgA, and Total IgA
Also known as: Deamidated Gliadin, Endomysial IgA Antibodies
Use
Aid in the diagnosis of gluten-sensitive enteropathies
Special Instructions
Not provided.
Limitations
The test might not detect all cases of celiac disease, as it primarily identifies specific antibodies. False negatives may occur, particularly if the patient has already eliminated gluten from their diet or possesses selective IgA deficiency. Consider results in conjunction with clinical findings and consider additional tests or biopsies if necessary. The presence of antibodies in the serum will decline with the exclusion of gluten from the diet, potentially impacting monitoring results. There may be variability in results depending on individual patient factors, and additional confirmatory tests are sometimes required to conclusively diagnose the condition.
Methodology
Immunoassay (ELISA)
Biomarkers
LOINC Codes
- 94493-4 - Celiac IgA + HLA + Sero Bld/T
- 58709-7 - Gliadin peptide IgA Ser-aCnc
- 58710-5 - Gliadin peptide IgG Ser-aCnc
- 31017-7 - tTG IgA Ser-aCnc
- 32998-7 - tTG IgG Ser-aCnc
- 10362-2 - Endomysium IgA Ser Ql
- 2458-8 - IgA SerPl-mCnc
Result Turnaround Time
3-5 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
3 mL
Minimum Volume
2.25 mL
Container
Red-top tube or gel-barrier tube
Storage Instructions
Room temperature
Causes for Rejection
Hemolysis; lipemia; gross bacterial contamination
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 14 days |
| Refrigerated | 14 days |
| Frozen | 14 days |
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