Chromosome Analysis, Chorionic Villi Biopsy
Also known as: CVS Prenatal Karyotyping, Chromosome Analysis
Use
Determine fetal karyotype
Special Instructions
Not provided.
Limitations
This test's performance characteristics were determined by Labcorp and have not been cleared or approved by the Food and Drug Administration. This limitation highlights that while the test can provide significant insights, it may not cover all potential chromosomal anomalies, especially those that fall beyond the resolution limits of cytogenetic techniques.
Methodology
Chromosomal / Cytogenetics (Karyotype)
Biomarkers
Chromosome Chromosomal Analysis
Chromosome
LOINC Codes
- 62350-4 - Chrom analy pnl CVS G-banded
- 64089-6 - Cells counted CVS
- 64086-2 - Cells analyzed CVS
- 64085-4 - Cells karyotyped.total CVS
- 64087-0 - ISCN band level CVS Ql
- 33774-1 - Karyotyp CVS
- 64088-8 - Karyotyp CVS
- 31208-2 - Specimen source
- 48672-0 - Clinical cytogeneticist Spec
- 11502-2 - Laboratory report
Result Turnaround Time
6-10 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (Fresh)
Volume
20 to 30 mg
Minimum Volume
5 mg
Container
CVS transport tube (a sterile specimen container with transport medium)
Collection Instructions
Specimen is collected in a syringe (transabdominal) or catheter (transcervical) and transferred by flushing with the media from the sterile container back into it. Wash with sterile saline solution (NaCl 0.95%) containing sodium heparin (two to three drops of sodium heparin in 10 mL of saline) before transferring into the CVS transport tube using a sterile Pasteur pipette or fine needle forceps. Multiple pregnancy samples should be labeled and placed in separate transport containers.
Storage Instructions
Maintain specimen at room temperature and transport immediately to the cytogenetics laboratory. Refrigerate if sterility is questioned or if the sample cannot be shipped within 24 hours. Do not freeze.
Causes for Rejection
Suitability of the specimen is determined by the Cytogenetics laboratory upon receipt. No villi, frozen specimens, and specimens in fix cannot be processed.
Other tests from different labs that may be relevant