Clomipramine
Also known as: Anafranil®
Use
Evaluate toxicity; monitor therapeutic levels
Special Instructions
Not provided.
Limitations
The LC/MS-MS methodology was developed and its performance characteristics determined by LabCorp, but it is not cleared or approved by the FDA. Metabolism of clomipramine may be dose-related and subject to enzyme inhibition from medications like valproic acid, which could lead to elevated clomipramine levels and potential seizures.
Methodology
Mass Spectrometry
Biomarkers
Clomipramine
AnalyteNorclomipramine
Analyte
LOINC Codes
- 3491-8 - clomiPRAMINE SerPl-mCnc
- 3491-8 - clomiPRAMINE SerPl-mCnc
- 3536-0 - Norclomipramine SerPl-mCnc
- 3493-4 - clomiPRAMINE+Nor SerPl-mCnc
Result Turnaround Time
2-5 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.3 mL
Container
Red-top tube, lavender-top (EDTA) tube, or green-top (heparin) tube
Collection Instructions
Transfer separated serum or plasma to a plastic transport tube. For therapeutic monitoring, collect specimen immediately prior to next dose.
Storage Instructions
Maintain specimen at room temperature.
Causes for Rejection
Gel-barrier tube
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 67 hours |
| Refrigerated | 14 days |
| Frozen | 14 days |
Other tests from different labs that may be relevant